About
Research Activities
The Biological Irradiation Core provides investigators with the ability to examine the effects of radiation treatment upon particular models such as yeast, fruit flies, nematodes, zebra fish, mammalian cells, and small animals. This provides investigators the capability to understand the effect of ionizing radiation on critical cellular responses, such as DNA repair, cellular proliferation and inflammation. In addition, investigators will be able to develop novel therapies using combination treatments of irradiation and small molecules.
In vitro studies:
•cultured mammalian cells
•establishment of feeder layers
•induction of DNA strand breaks
•cell survival studies
In vivo preclinical studies:
- rodent tumor therapy studies
- spontaneous animal tumor studies
- normal tissue radiation tolerance and pathophysiology studies
- radiation physics/development studies